A dissolving microneedle system incorporating dexamethasone-loaded nanoparticles has been developed to enhance therapeutic outcomes for inflammatory skin diseases by offering controlled drug delivery and improved patient compliance. Advances in Transdermal…

The convergence of polymer science and nanotechnology has spurred remarkable advancements in healthcare, enabling targeted, efficient, and multifunctional therapeutic strategies. Recent research reveals the versatile applications of polymeric nanoparticles across…

A Historical Challenge: Tackling Chronic Wounds Diabetic wounds, often plagued by biofilm infections and persistent inflammation, have long posed a challenge to the medical field. Traditional treatments—ranging from aggressive debridement…

Researchers have developed anisamide-tethered lipid nanoparticles (AA-lipidoids) that significantly improve RNA delivery to activated hepatic stellate cells, offering a promising therapeutic strategy for liver fibrosis. Background: Understanding Liver Fibrosis Liver…

The Evolution of Cancer Therapies Cancer treatment has long challenged researchers, with metastases—the spread of cancer cells to distant organs—accounting for the majority of cancer-related deaths. Over decades, photodynamic therapy…

According to a phase I clinical trial published in Nature, a novel personalized RNA neoantigen vaccine combined with immunotherapy and chemotherapy has demonstrated significant potential to delay pancreatic cancer. Background…

A Historical Perspective on Immunotherapy Immunotherapy has revolutionized cancer treatment by harnessing the body’s immune system to target malignancies. For prostate cancer patients, especially those with bone metastases, immunotherapy offers…

Researchers have developed a novel CSP-LB hydrogel combining MgFe-layered double hydroxide nanosheets with dual growth factors, offering significant advances in bone defect treatment. Context of Hepatocellular Carcinoma: Challenges in Treatment…