Introduction: Navigating the Challenges of Inflammatory Bowel DiseaseInflammatory bowel diseases (IBDs), including ulcerative colitis (UC) and Crohn’s disease (CD), present persistent challenges due to their chronic nature and significant impact…

Introduction: A New Dawn for Light-Activated Drug DeliveryAdvancements in cancer therapy have witnessed a paradigm shift with the emergence of light-activated drug delivery systems, combining precision with minimized side effects.…

A study demonstrates that GalNAc-Lipid nanoparticles can achieve efficient liver-targeted delivery of CRISPR base editing therapy, offering a potential option for treating familial hypercholesterolemia and other liver diseases. Background Challenges…

A dissolving microneedle system incorporating dexamethasone-loaded nanoparticles has been developed to enhance therapeutic outcomes for inflammatory skin diseases by offering controlled drug delivery and improved patient compliance. Advances in Transdermal…

The convergence of polymer science and nanotechnology has spurred remarkable advancements in healthcare, enabling targeted, efficient, and multifunctional therapeutic strategies. Recent research reveals the versatile applications of polymeric nanoparticles across…

A Historical Challenge: Tackling Chronic Wounds Diabetic wounds, often plagued by biofilm infections and persistent inflammation, have long posed a challenge to the medical field. Traditional treatments—ranging from aggressive debridement…

Researchers have developed anisamide-tethered lipid nanoparticles (AA-lipidoids) that significantly improve RNA delivery to activated hepatic stellate cells, offering a promising therapeutic strategy for liver fibrosis. Background: Understanding Liver Fibrosis Liver…

The Evolution of Cancer Therapies Cancer treatment has long challenged researchers, with metastases—the spread of cancer cells to distant organs—accounting for the majority of cancer-related deaths. Over decades, photodynamic therapy…