Preclinical Proof of Concept for VivoVec: An Approach to CAR T-Cell Engineering

Editor: Nina Researchers introduce UB-VV100, an innovative lentiviral vector platform for in vivo CAR T-cell engineering that effectively targets B-cell malignancies while eliminating the need for ex vivo manufacturing and…

Advancements in Nerve Repair: A Multifunctional Conduit for Peripheral Nerve Regeneration

Editor: Nina Researchers develop a multifunctional nerve guidance conduit integrating a density gradient of aFGF-encapsulated collagen nanoparticles and electrospun fibers to enhance peripheral nerve regeneration and functional recovery. Key Preview…

Targeted Nanoimmunotherapy: Reprogramming Synovial Inflammatory Macrophages for Rheumatoid Arthritis Treatment

Editor: Nina Scientists develop an efferocytosis-informed nanoimitator that targets synovial inflammatory macrophages to reprogram immune responses and mitigate rheumatoid arthritis symptoms. Key Preview Introduction Rheumatoid arthritis (RA) is a prevalent…

Hybrid Exosomes Enhance Paclitaxel Delivery for Colorectal Cancer Therapy

Editor: Tiffany A new hybrid exosome system developed by Jilin University researchers enhances paclitaxel delivery, significantly suppressing colorectal tumor growth and activating the immune response in a mouse model. Key…

New Method Uses Bacteria as Microrobots to Target Tumors More Precisely

Editor: Tiffany A new method called torque-focusing uses magnetic fields to precisely guide bacteria-based microrobots to tumor sites, improving drug delivery accuracy and reducing off-target effects in cancer treatment. Key…

Innovative Drug Delivery: Combining Microneedles with Nanosuspension and Co-grinding for Enhanced Ketoprofen Transdermal Application

Editor: Nina Scientists develop a transdermal drug delivery system combining dissolving microneedles with nanosuspension and co-grinding techniques to improve the solubility and delivery of ketoprofen. Key Preview Research Question The…

Novel Lactoferrin-Coated Selenium Nanoparticles Show Efficacy in Targeting Cancer Cells

Editor: Tiffany Researchers have developed an innovative combination of lactoferrin-coated selenium nanoparticles that demonstrates significant anticancer activity, selectively targeting various human cancer cells while sparing healthy tissues. Key Highlights Cancer…

3D Printing Technology Enhances Drug Delivery for Wound Healing

Editor: Sarah In recent years, the field of personalized medicine has advanced significantly, and one of the promising innovations in this area is the integration of 3D printing technology in…