Innovative Dual-Functional Nanoparticles Target YY1 to Enhance Immunotherapy for Hepatocellular Carcinoma
Editor: Nina Scientists develop dual-functional mesoporous silica nanoparticles loaded with Isorhamnetin and anti-PD-L1 antibodies to enhance immune checkpoint inhibition and inhibit YY1-mediated tumor progression in hepatocellular carcinoma. Key Preview Introduction…
Innovative Nanoparticle Strategy Enhances High-Intensity Focused Ultrasound for Cancer Treatment
Editor: Tiffany A novel approach combining high-intensity focused ultrasound with biomimetic oxygen-carrying nanoparticles significantly enhances tumor destruction and immune response in cancer treatment, addressing key challenges in traditional therapies. Key…
Biodegradable Polyphosphoester Micelles: Dual-Function Nanocarriers for Background-Free 31P MRI and Drug Delivery
Editor: Nina Scientists develop biodegradable polyphosphoester micelles that function as dual agents for background-free magnetic resonance imaging and effective drug delivery in cancer treatment. Key Preview Introduction In recent years,…
M1 Macrophage-Derived Exosomes Loaded with RSL3 Enhance Ferroptosis and Modulate the Tumor Microenvironment for Improved Cancer Immunotherapy
Editor: Tiffany A novel therapeutic strategy using M1 macrophage-derived exosomes loaded with the ferroptosis inducer RSL3 has been shown to effectively accumulate in tumors, induce ferroptosis, and reprogram the immunosuppressive…
Cloud α AX12: A Cutting-Edge Lung-on-Chip Inhalation Platform for Nanoparticle Toxicity and Drug Efficacy Testing
Editor: Nina Scientists develop the Cloud α AX12 inhalation platform, an innovative lung-on-chip system combined with cloud-based aerosol exposure technology, to accurately assess inhalation toxicity and drug efficacy in respiratory…
Prebiotic Nanoparticle Enhances Capecitabine Delivery and Modulates Gut Microbiota for Improved Colorectal Cancer Therapy
Editor: Tiffany Researchers have developed a prebiotic nanoparticle that significantly improves the delivery of capecitabine to colorectal cancer tumors while modulating gut microbiota to enhance anti-tumor immunity, offering a promising…
Fluorinated Polyamidoamine Dendrimers Enhance miR-23b Delivery for Effective Treatment of Rheumatoid Arthritis
Editor: Nina Scientists develop fluorinated polyamidoamine dendrimer-mediated nanoparticles for targeted delivery of microRNA-23b, effectively reducing inflammation and promoting apoptosis in rheumatoid arthritis models. Key Preview Research QuestionThe study investigates whether…
New Inhalation Platform Enhances Preclinical Research for Respiratory Diseases
Editor: Tiffany Researchers have unveiled an innovative multiplex inhalation platform, the Cloud α AX12, designed to accurately model aerosol delivery in a dynamic lung-on-chip environment, enhancing the study of inhalation…