Synergistic pH-Responsive Serum Albumin-Based Drug Delivery System for Targeted NSCLC Therapy
Key Preview Introduction Non-small cell lung cancer (NSCLC) represents a significant health challenge, accounting for approximately 85% of all lung cancer cases and leading to high mortality rates worldwide. Characterized…
New Nanocomposite Enhances Metformin’s Efficacy in Type 2 Diabetes and Obesity
Editor: Tiffany A new nanoconjugate combining hyaluronic acid and graphene oxide quantum dots has been developed to improve metformin’s delivery and effectiveness in treating inflammation associated with type 2 diabetes…
Targeted Gene Therapy for Liver Cancer Using Nanoparticle Delivery via Hepatic Artery
Editor: Tiffany Researchers at Johns Hopkins University have developed a novel gene therapy approach using biodegradable nanoparticles delivered directly to liver tumors via the hepatic artery, achieving significantly higher tumor…
Targeting Mitochondrial DNA with Rh-Mito to Enhance Cancer Immunotherapy
Editor: Tiffany Researchers have developed Rh-Mito, a small molecule that targets mitochondrial DNA to activate the cGAS-STING pathway, enhancing cancer immunotherapy by triggering immune responses and altering epigenetic regulation. Key…
Innovative Carbon Dots-Based Therapy Offers New Hope Against Drug-Resistant Lung Cancer
Editor: Tiffany Researchers have developed a carbon dots-based nanozyme that co-delivers doxorubicin and siRNA to effectively address drug-resistant lung cancer, potentially enhancing treatment options for affected patients. Key Highlights Context…
Innovative Approach to Colorectal Cancer Treatment: Combining Gut Microbiota Modulation with Chemotherapy
Editor: Nina Researchers create a capecitabine-loaded prebiotic nanoparticle that enhances colorectal cancer treatment through gut microbiota modulation and improved drug delivery, leading to increased therapeutic efficacy and reduced side effects.…
A New Approach to Enhancing Immune Response in Pancreatic Cancer Treatment
Editor: Tiffany Researchers have developed a novel hydrogel microsphere vaccine that significantly boosts immune responses against pancreatic cancer following ablation therapy, potentially improving patient survival rates. Key Highlights Pancreatic Cancer…
Fatostatin Induces Ferroptosis in Glioblastoma: A Promising New Approach
Editor: Nina Scientists reveal that fatostatin induces ferroptosis in glioblastoma cells by inhibiting the AKT/mTORC1/GPX4 signaling pathway and develop a p28-functionalized PLGA nanoparticle delivery system to enhance targeted treatment efficacy.…