AMD Treatment: High-Capacity Mesoporous Silica Nanocarriers Deliver siRNA to Retinal Cells
Editor: Nina Scientists develop large pore mesoporous silica nanoparticles as an innovative drug delivery system for effective siRNA targeting of VEGF in retinal cells to enhance treatment for age-related macular…
Systemic Leptin-Mediated Delivery of Fas-Blocking Peptide Reduces Apoptosis in Ischemic Stroke
Editor: Tiffany A leptin-conjugated Fas-blocking peptide, delivered systemically, inhibits apoptosis and reduces brain damage in animal models of ischemic stroke by targeting Fas-expressing regions, offering a potential new treatment strategy.…
Shortwave-Infrared Probes: A New Frontier in Cancer Vaccine Tracking
Editor: Nina Scientists develop a shortwave-infrared light-emitting nanoparticle-based nanovaccine to enable real-time tracking of immune responses and effective eradication of cancer tumors in vivo. Key Preview Research Question This study…
New Hope for Glioblastoma: Combining Temozolomide and Doxorubicin
Editor: Tiffany Researchers have discovered that combining temozolomide and doxorubicin significantly enhances the effectiveness of glioblastoma treatment, particularly in drug-resistant cells, offering new hope for patients battling this challenging cancer.…
Strontium-Doped Bioactive Glass Coating Enhances Antibacterial Properties of Orthopedic Implants
Editor: Nina Scientists develop a strontium-doped bioactive glass and polydopamine functionalized polyetheretherketone implant system to enhance antibacterial efficacy and promote tissue repair against methicillin-resistant Staphylococcus aureus infections through photothermal therapy…
Tetrahedral Framework Nucleic Acids/Hyaluronic Acid-Methacrylic Anhydride Hybrid Hydrogel for Infected Wound Healing
Editor: Tiffany Introduction Infected wounds, particularly in the oral and maxillofacial regions, pose a significant challenge in clinical settings. These wounds often arise from trauma that exposes skin and oral…
Microbial Nanofactories: Boosting Cancer Immunotherapy with Biogenic Prussian Blue
Editor: Nina Scientists develop a mitochondria-targeting nanoplatform, MiBaMc, synthesized from Prussian blue nanoparticles using Shewanella oneidensis MR-1, to enhance checkpoint blockade immunotherapy and achieve significant tumor growth inhibition in triple-negative…
Ionizable Lipid Nanoparticle-Mediated TRAIL mRNA Delivery to the Tumor Microenvironment Inhibits Colon Cancer Progression
Editor: Tiffany Researchers have developed an ionizable lipid nanoparticle (LNP) platform to deliver TRAIL mRNA directly to the tumor microenvironment, effectively inducing tumor cell death and inhibiting colon cancer progression,…