Revolutionizing Pain Relief: A Breakthrough in Transdermal Delivery of Ketoprofen Using Microneedles
Editor: Nina Researchers develop a dissolving microneedle system combined with nanosuspension and co-grinding techniques to enhance the transdermal delivery of ketoprofen, improving its solubility and therapeutic efficacy for osteoarthritis management.…
Innovative Hydrogel-Based Delivery System Enhances Itaconate’s Therapeutic Potential for Osteoarthritis Treatment
Editor: Tiffany Researchers have developed a novel drug delivery system that enables the sustained and targeted release of itaconate, a cell-impermeable molecule, directly into joint cells, showing significant promise in…
Enhancing Skin Cancer Treatment: Solid Lipid Nanoparticles for Sustained Release and Improved Cytotoxicity of 5-Fluorouracil
Editor: Nina Scientists develop a solid lipid nanoparticle system for enhanced delivery and sustained release of 5-fluorouracil, significantly improving its cytotoxicity against skin melanoma and squamous cell carcinoma while ensuring…
Novel Intranasal Propranolol Delivery System Enhances Brain Targeting for Migraine Treatment
Editor: Tiffany A new study introduces an intranasal nanogel delivery system for propranolol, improving its brain availability and presenting a promising option for enhancing migraine treatment efficacy. Key Highlights Migraine…
Softness-Enhanced Macrophage-Mediated Nanosystems for Targeted Therapy of Acute Lung Injury
Editor: Nina Scientists develop soft, macrophage-targeting apoptotic-cell-inspired nanosystems loaded with N-acetylcysteine to enhance therapeutic efficacy and promote lung repair in acute lung injury. Key Preview Introduction Acute lung injury (ALI)…
Innovative Supramolecular Peptide Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma
Editor: Tiffany A newly designed supramolecular peptide, sBBI&PDP, effectively targets both β-catenin and PD-L1, enhancing immunotherapy outcomes for patients with hepatocellular carcinoma (HCC). Key Highlights Context of Hepatocellular Carcinoma Treatment…
New Complexation Technique Boosts Solubility and Efficacy of Hepatoprotector Icariin
Editor: Tiffany A recent study demonstrates that complexing the natural hepatoprotector icariin with hydroxypropyl-γ-cyclodextrin significantly enhances its solubility and bioavailability, indicating improved therapeutic potential for liver health. Key Highlights Icariin:…
Innovative Nano-Assemblies of Amphotericin B Show Promise Against Visceral Leishmaniasis with Reduced Toxicity
Editor: Nina Scientists develop Amphotericin B nano-assemblies using mango pulp extract to significantly reduce toxicity and enhance therapeutic efficacy against visceral leishmaniasis. Key Preview Research QuestionThe study primarily addresses the…