Softness-Enhanced Macrophage-Mediated Nanosystems for Targeted Therapy of Acute Lung Injury
Editor: Nina Scientists develop soft, macrophage-targeting apoptotic-cell-inspired nanosystems loaded with N-acetylcysteine to enhance therapeutic efficacy and promote lung repair in acute lung injury. Key Preview Introduction Acute lung injury (ALI)…
Innovative Supramolecular Peptide Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma
Editor: Tiffany A newly designed supramolecular peptide, sBBI&PDP, effectively targets both β-catenin and PD-L1, enhancing immunotherapy outcomes for patients with hepatocellular carcinoma (HCC). Key Highlights Context of Hepatocellular Carcinoma Treatment…
New Complexation Technique Boosts Solubility and Efficacy of Hepatoprotector Icariin
Editor: Tiffany A recent study demonstrates that complexing the natural hepatoprotector icariin with hydroxypropyl-γ-cyclodextrin significantly enhances its solubility and bioavailability, indicating improved therapeutic potential for liver health. Key Highlights Icariin:…
Innovative Nano-Assemblies of Amphotericin B Show Promise Against Visceral Leishmaniasis with Reduced Toxicity
Editor: Nina Scientists develop Amphotericin B nano-assemblies using mango pulp extract to significantly reduce toxicity and enhance therapeutic efficacy against visceral leishmaniasis. Key Preview Research QuestionThe study primarily addresses the…
New Delivery System for Fisetin Shows Promise Against Severe Acute Pancreatitis
Editor: Nina Researchers formulate lipid polymer hybrid nanoparticles loaded with Fisetin to enhance its solubility and therapeutic efficacy in treating severe acute pancreatitis, demonstrating significant protective effects against pancreatic damage…
Silencing miR-21 in Sensory Neurons Alleviates Neuropathic Pain by Modulating Macrophage Polarization
Editor: Tiffany A new study reveals that silencing miR-21 in sensory neurons reduces neuropathic pain by promoting an anti-inflammatory phenotype in macrophages, offering a potential new therapeutic target for this…
New Research Identifies Exosomal lncRNA MLETA1 as a Key Player in Lung Cancer Metastasis
Editor: Tiffany A recent study identifies lnc-MLETA1 as a pivotal exosomal long noncoding RNA that promotes lung cancer metastasis by enhancing cell migration and invasion through specific microRNA interactions. Key…
Smart Hydrogels for Skin Relief: A Nanotech Boost to Atopic Dermatitis Therapy
Editor: Nina Researchers formulate a hyaluronic acid hydrogel incorporating resveratrol-loaded chitosan nanoparticles to enhance therapeutic efficacy and provide sustained release for the treatment of atopic dermatitis. Key Preview Research QuestionThis…