Enhancing Cellular Uptake and 19F-MRI Sensitivity through Protein Corona Formation on PLGA Nanoparticles for Non-Invasive Cell Tracking
Researchers investigate the role of protein corona formation on the surface of 19F-labeled PLGA nanoparticles, demonstrating how surface modifications enhance cellular uptake and improve 19F-MRI sensitivity for non-invasive cell tracking…
Transferrin-Decorated PLGA Nanoparticles Loaded with Organoselenium Compound for Targeted Overcoming of Multidrug Resistance in Cancer Therapy
This study demonstrates the development of transferrin-decorated PLGA nanoparticles loaded with an organoselenium compound as a targeted drug delivery system that effectively sensitizes multidrug-resistant tumor cells, enhancing cancer therapy through…
Advancements in Intratumoral Transport Mechanisms for Nanomedicine: Enhancing Targeted Cancer Therapies Through Active Movement, Intelligent Release, and Multimodal Approaches
Introduction: Enhancing Nanomedicine Transport for Targeted Cancer Therapy Recent advancements in intratumoral transport mechanisms of nanomedicines are revolutionizing cancer therapy by overcoming traditional barriers such as inefficient drug delivery, low…
Development of Doxorubicin-Loaded Silica and Nylon-Coated Silica Nanoparticles for pH-Responsive Cancer Drug Delivery
Editor:Nina This study presents the synthesis and characterization of doxorubicin-loaded silica and nylon-coated silica nanoparticles (SiNPs-Nylon) for targeted cancer treatment, demonstrating high drug loading capacity, pH-sensitive drug release, and enhanced…
Polymeric Nanoparticle-Driven Delivery of Ruthenium Complexes: Enhancing Efficacy and Reducing Toxicity in High-Grade Ovarian Cancer
This study develops and evaluates a novel polymeric nanoparticle system for the delivery of ruthenium-based cytotoxic agents, demonstrating enhanced tumor targeting, reduced off-target toxicity, and promising efficacy against high-grade ovarian…
Asiaticoside May Alleviate Symptoms of Alzheimer’s Disease by Reducing Inflammation and Promoting Synaptic Repair
Author: Tiffany A recent study published in the International Journal of Molecular Sciences suggests that Asiaticoside (AS) could potentially reduce symptoms of Alzheimer’s disease (AD) by targeting inflammation and supporting…
Optimizing Immune Responses in Self-Amplifying RNA Vaccines: The Impact of Formulation on Inflammation and Antigen Expression
Editor: Nina This study investigates how different formulations of self-amplifying RNA (saRNA) vaccines influence immune responses by modulating inflammation and antigen expression, revealing that lipid nanoparticle formulations elicit the strongest…
Development of Atomoxetine-Loaded in Situ Gel for Enhanced Dementia Treatment
Author: Tiffany Researchers have designed an atomoxetine-loaded nanostructured lipid carrier (NLC) in situ gel, demonstrating potential for improving drug delivery to the brain via the nasal route, providing a new…