Novel Intranasal Propranolol Delivery System Enhances Brain Targeting for Migraine Treatment
Editor: Tiffany A new study introduces an intranasal nanogel delivery system for propranolol, improving its brain availability and presenting a promising option for enhancing migraine treatment efficacy. Key Highlights Migraine…
Softness-Enhanced Macrophage-Mediated Nanosystems for Targeted Therapy of Acute Lung Injury
Editor: Nina Scientists develop soft, macrophage-targeting apoptotic-cell-inspired nanosystems loaded with N-acetylcysteine to enhance therapeutic efficacy and promote lung repair in acute lung injury. Key Preview Introduction Acute lung injury (ALI)…
Innovative Supramolecular Peptide Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma
Editor: Tiffany A newly designed supramolecular peptide, sBBI&PDP, effectively targets both β-catenin and PD-L1, enhancing immunotherapy outcomes for patients with hepatocellular carcinoma (HCC). Key Highlights Context of Hepatocellular Carcinoma Treatment…
Amphiphilic Polypeptides Enhance Paclitaxel Delivery Against Lung Cancer
Editor: Nina Scientists synthesize amphiphilic polypeptides via post-polymerization modification of poly(α,L-glutamic acid) to create effective nanoparticles for the targeted delivery of hydrophobic drugs like paclitaxel, enhancing anti-cancer efficacy while minimizing…
New Complexation Technique Boosts Solubility and Efficacy of Hepatoprotector Icariin
Editor: Tiffany A recent study demonstrates that complexing the natural hepatoprotector icariin with hydroxypropyl-γ-cyclodextrin significantly enhances its solubility and bioavailability, indicating improved therapeutic potential for liver health. Key Highlights Icariin:…
Innovative Nano-Assemblies of Amphotericin B Show Promise Against Visceral Leishmaniasis with Reduced Toxicity
Editor: Nina Scientists develop Amphotericin B nano-assemblies using mango pulp extract to significantly reduce toxicity and enhance therapeutic efficacy against visceral leishmaniasis. Key Preview Research QuestionThe study primarily addresses the…
New Delivery System for Fisetin Shows Promise Against Severe Acute Pancreatitis
Editor: Nina Researchers formulate lipid polymer hybrid nanoparticles loaded with Fisetin to enhance its solubility and therapeutic efficacy in treating severe acute pancreatitis, demonstrating significant protective effects against pancreatic damage…
Silencing miR-21 in Sensory Neurons Alleviates Neuropathic Pain by Modulating Macrophage Polarization
Editor: Tiffany A new study reveals that silencing miR-21 in sensory neurons reduces neuropathic pain by promoting an anti-inflammatory phenotype in macrophages, offering a potential new therapeutic target for this…