New Optical Method Enables Drug Delivery Across Brain Tumor Barrier, Renewing Potential for Glioblastoma Therapies
Editor:Sarah A key obstacle in glioblastoma therapy is the BBTB, which blocks over 98% of chemotherapy drugs from entering the brain, rendering many potentially effective drugs unusable. OptoBBTB addresses this…
Enhancing Antimicrobial Peptide Delivery via Silica Entrapment for Safer and More Stable Therapeutic Applications
Editor: Sarah As global antibiotic resistance continues to intensify, antimicrobial peptides (AMPs) have gained attention as potential alternatives to traditional antibiotics. These peptides, naturally present in many organisms, possess broad-spectrum…
Low-Energy Nebulization Method Preserves mRNA Vaccine Integrity for Respiratory Delivery
Researchers at the University of Amsterdam and affiliated institutions have developed a low-energy nebulization technique designed to deliver mRNA vaccines, such as those targeting SARS-CoV-2, via the respiratory tract. This…
Microfluidic Technology Enhances Drug Delivery: A Step Toward More Efficient and Safer Treatments
Editor: Sarah A recent study explored the application of microfluidic technology for the synthesis of metal-organic frameworks (MOFs), specifically Zeolitic Imidazole Framework-67 (ZIF-67) and its bimetallic variant, Zn-ZIF-67. The study…
Systemic Leptin-Mediated Delivery of Fas-Blocking Peptide Reduces Apoptosis in Ischemic Stroke
Editor: Tiffany A leptin-conjugated Fas-blocking peptide, delivered systemically, inhibits apoptosis and reduces brain damage in animal models of ischemic stroke by targeting Fas-expressing regions, offering a potential new treatment strategy.…
Shortwave-Infrared Probes: A New Frontier in Cancer Vaccine Tracking
Editor: Nina Scientists develop a shortwave-infrared light-emitting nanoparticle-based nanovaccine to enable real-time tracking of immune responses and effective eradication of cancer tumors in vivo. Key Preview Research Question This study…
New Hope for Glioblastoma: Combining Temozolomide and Doxorubicin
Editor: Tiffany Researchers have discovered that combining temozolomide and doxorubicin significantly enhances the effectiveness of glioblastoma treatment, particularly in drug-resistant cells, offering new hope for patients battling this challenging cancer.…
Strontium-Doped Bioactive Glass Coating Enhances Antibacterial Properties of Orthopedic Implants
Editor: Nina Scientists develop a strontium-doped bioactive glass and polydopamine functionalized polyetheretherketone implant system to enhance antibacterial efficacy and promote tissue repair against methicillin-resistant Staphylococcus aureus infections through photothermal therapy…