High-Throughput Barcoding Identifies Lipid Nanoparticles for Lung-Specific mRNA Delivery
Editor: Tiffany Researchers at the University of Pennsylvania have developed a high-throughput barcoding technology that successfully identifies lipid nanoparticles for effective mRNA delivery to lung tissues, potentially improving treatments for…
Innovative Nanomedicine Enhances Anti-PD-L1 Therapy for Triple-Negative Breast Cancer
Editor: Nina Scientists develop a multifunctional nanoparticle system that selectively depletes NADPH in tumor cells while enhancing anti-PD-L1 therapy and reprogramming the tumor microenvironment to improve treatment outcomes for triple-negative…
Gelated Macrophages Offer New Strategy for Treating Inflammatory Diseases
Editor: Tiffany A new study demonstrates that engineered macrophages with preserved membrane structures can neutralize multiple inflammatory cytokines, showing promise in animal models of rheumatoid arthritis and acute pneumonia. Key…
Novel Nanocomposite Enhances Targeted Delivery of Chemotherapy and Gene Therapy for Cancer
Editor: Tiffany A newly developed nanocomposite combining amine-functionalized metal-organic frameworks with magnetic nanoparticles enables precise co-delivery of doxorubicin and pCRISPR to cancer cells, improving therapeutic efficacy and reducing toxicity. Key…
Cancer Therapy: pH-Responsive Curcumin Delivery Using L-Lysine Functionalized Mesoporous Silica Nanoparticles
Editor: Nina Scientists synthesize L-lysine functionalized mesoporous silica nanoparticles for pH-responsive delivery of curcumin, enhancing targeted cancer therapy and improving therapeutic efficacy. Key Preview Research Question The study investigates how…
Revolutionizing Brain Tumor Treatment: Nanostructured Lipid Carriers Boost Oral Bioavailability of Perillyl Alcohol
Editor: Nina Scientists enhance the oral bioavailability and brain biodistribution of perillyl alcohol by developing a nanostructured lipid carrier system, aiming to improve therapeutic outcomes for glioblastoma treatment. Key Preview…
Optimized Albumin Nanoparticles Enhance Silymarin’s Efficacy Against Hepatocellular Carcinoma
Editor: Tiffany A study demonstrates that optimized albumin nanoparticles significantly improve the bioavailability and anti-cancer efficacy of silymarin in treating hepatocellular carcinoma, utilizing a Quality by Design framework for formulation.…
Glioblastoma Treatment: Dual Peptide-Functionalized Nanoparticles Enhance Palbociclib Delivery Across the Blood-Brain Barrier
Editor: Nina Scientists develop dual-peptide functionalized nanoparticles to enhance blood-brain barrier penetration and cytotoxicity of Palbociclib in U87-MG glioblastoma cells for improved therapeutic outcomes. Key Preview Introduction Glioblastoma is one…