Application of Stimuli-Responsive Nanomedicines for the Treatment of Ischemic Stroke
Editor: Sarah Ischemic stroke (IS) is a major cause of death and long-term disability around the world. It results from restricted blood flow to the brain, leading to the death…
Novel P-Selectin-Targeted Nanocarriers Enhance Drug Delivery for Medulloblastoma Treatment by Crossing the Blood-Brain Barrier
A recent study shows that P-selectin-targeted nanocarriers can effectively cross the blood-brain barrier to deliver the cancer drug vismodegib directly to medulloblastoma tumors, potentially reducing harmful side effects. Key Highlights:…
Exosome-Based Therapy Shows Promise in Alleviating Alcohol-Associated Liver Injury in Mice
Editor: Nina This study demonstrates that exosome-based delivery of super-repressor IκBα (Exo-srIκB) effectively mitigates alcohol-associated liver injury in mice by targeting inflammation in Kupffer cells, highlighting its potential as a…
Potential of Stem Cell-Derived Exosomes in Treating Polycystic Ovary Syndrome
Author: Tiffany A recent study has indicated that exosomes derived from human mesenchymal stem cells could present a new therapeutic option for treating Polycystic Ovary Syndrome (PCOS), a condition that…
Development of Tumor-Specific Gene Nanomedicine to Improve T-Cell Recruitment and Activation in Melanoma Treatment
Author: Tiffany A recent study has developed a tumor-specific gene nanomedicine that enhances T-cell recruitment and activation, leading to improved effectiveness in the treatment of melanoma through immunotherapy. Key Highlights:…
New Vaccine Design Promises Broad Protection Against SARS-CoV-2 and Related Viruses
This study presents a computationally designed antigen, T2_17, which elicits broad humoral immune responses against SARS-CoV-2 and related sarbecoviruses, demonstrating potential for effective vaccine development to combat zoonotic spillovers and…
New Approach to Combat Paclitaxel-Resistant Lung Cancer: A Dual Nanoparticle Strategy
Editor: Nina This study presents a novel combination therapy using cabazitaxel-loaded human serum albumin nanoparticles and TGFβ-1 siRNA lipid nanoparticles, demonstrating enhanced efficacy and reduced toxicity in treating paclitaxel-resistant non-small…