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Development of Atomoxetine-Loaded in Situ Gel for Enhanced Dementia Treatment
Author: Tiffany Researchers have designed an atomoxetine-loaded nanostructured lipid carrier (NLC) in situ gel, demonstrating potential for improving drug delivery to the brain via the nasal route, providing a new…
Exosomal circCABIN1 Drives Temozolomide Resistance in Glioblastoma Therapy
Researchers have identified exosomal circCABIN1 as a key factor contributing to temozolomide resistance in glioblastoma, offering potential pathways for improving treatment strategies. Key Highlights: Challenges in Treating Glioblastoma Glioblastoma Overview…
A pH-Responsive Nanomedicine for Enhanced Lung Cancer Immunotherapy through Dual Immune Activation
Editor:Nina This study presents a novel pH-responsive nanomedicine that co-delivers a calcium channel inhibitor (TTA-Q6) and a CD47 inhibitor (RRX-001) to reprogram the tumor microenvironment, activating both innate and adaptive…
Smart Hydrogels: A New Tool in Fighting Wound Infections
Editor: Sarah Could a new material redefine how we treat infected wounds? Researchers from Xi’an Jiaotong University have developed a bacteria-responsive, self-activating antibacterial hydrogel that offers a promising solution for…
NO Nanoparticle Therapy Shows Potential in Pediatric CKD Treatment
Author: Tiffany A recent study highlights the effectiveness of GSNO-loaded nanoparticles in controlling blood pressure and preserving kidney function in young rats with CKD, offering new insights for pediatric care.…
Advancements in RNA-Based Vaccines for Tuberculosis: A Preclinical Evaluation of Replicating RNA (repRNA) Platforms
Editor:Nina Key Preview Research Question Research Design and Strategy Method Key Results Significance of the Research Introduction The emergence of tuberculosis as a leading cause of death from infectious diseases…
Development of mRNA Vaccines Encoding Fusion Proteins of Monkeypox Virus Antigens: A Preclinical Study Demonstrating Robust Protection Against Lethal Orthopoxvirus Challenges
Editor: Nina Key Preview Research Question Research Design and Strategy Method Key Results Significance of the Research Introduction The emergence of mpox has highlighted an urgent need for effective vaccination…
Tackling Antibiotic Resistance with an Innovative Vanadium-Based MXene Nanoplatform
Editor: Sarah The Growing Challenge of Antibiotic Resistance Antibiotic resistance is one of the most pressing global health challenges, driven by the overuse and misuse of antibiotics and the adaptive…